A woman in Texas spent 10 years stitching a scale replica of the Sistine Chapel, of her own design. It took her 700 hours to design it. It took 2,872 hours to stitch the piece, which includes 628,296 stitches in 1,809 different color combinations. It measures 80" x 40", that's well over 6 feet x 3 feet to us mere mortals.
You can order the pattern here, but, really, you'd have to be high. It took Michaelangelo only 4 years to paint it. It took me about 12 minutes to photograph it.
(She's charging pennies for her labor; the 276-page work goes for $69.99. Or you can download the b&w version for $23.85. Patterns for individual panels are also available.)